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Empagliflozin, Metformin

ブランド:

• Empasmart Met

製造元:

• Healing Pharma

病衣:

• Diabetes

Empagliflozin and Metformin Tablets

What is Empagliflozin and Metformin?

Empagliflozin and Metformin contains a combination of empagliflozin and metformin. Empagliflozin and metformin are oral diabetes medicines that help control blood sugar levels. Empagliflozin works by helping the kidneys get rid of glucose from your bloodstream. Metformin lowers glucose production in the liver and also causes your intestines to absorb less glucose.

Empagliflozin and Metformin is used together with diet and exercise to improve blood sugar control in patients aged 10 years and older with type 2 diabetes mellitus.

Empagliflozin and Metformin is also used to lower the risk of death from heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease.

Empagliflozin and Metformin is not for treating type 1 diabetes.

Warnings

Empagliflozin and Metformin may cause a serious condition called lactic acidosis. Get emergency medical help if you have even mild symptoms such as: muscle pain or weakness, numb or cold feeling in your arms and legs, trouble breathing, stomach pain, nausea with vomiting, slow or irregular heartbeats, dizziness, or feeling very weak or tired.

Tell your doctor if you are sick with vomiting or diarrhea, or if you eat or drink less than usual.

In rare cases, this medicine can cause serious infections in the penis or vagina. Get medical help right away if you have burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, or if you don't feel well.

You should not use Empagliflozin and Metformin if you have moderate to severe kidney disease, if you are on dialysis, or diabetic ketoacidosis (call your doctor for treatment).

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Empagliflozin and Metformin.

Before taking this medicine

You should not use Empagliflozin and Metformin if you are allergic to empagliflozin or metformin, or if you have:

• severe kidney disease (or if you are on dialysis); or
• metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking this medicine. Be sure your caregivers know ahead of time that you are using Empagliflozin and Metformin.

To make sure Empagliflozin and Metformin is safe for you, tell your doctor if you have:

• liver or kidney disease;
• a bladder infection or urination problems;
• congestive heart failure, a heart attack or stroke;
• a genital infection (penis or vagina);
• problems with your pancreas, including surgery;
• if you are on a low salt diet; or
• if you are 65 or older.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Ask your doctor about your risk.

Follow your doctor's instructions about using Empagliflozin and Metformin if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy.

You should not use Empagliflozin and Metformin during the second or third trimester of pregnancy.

Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

Do not breastfeed while using Empagliflozin and Metformin.

Not approved for use by anyone younger than 18 years old.

How should I take Empagliflozin and Metformin?

Take Empagliflozin and Metformin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.

Take with meals.

Swallow the Empagliflozin and Metformin extended-release tablet whole and do not crush, chew, break, or dissolve it. Tell your doctor if you have trouble swallowing the tablet.

Your blood sugar will need to be checked often, and you may also need to test the level of ketones in your urine. Empagliflozin can cause life-threatening ketoacidosis (too much acid in the blood). Even if your blood sugar is normal, contact your doctor if a urine test shows that you have high ketones in the urine.

Blood sugar can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals.

Low blood sugar (hypoglycemia) can make you feel very hungry, dizzy, irritable, or shaky. To quickly treat hypoglycemia, eat or drink hard candy, crackers, raisins, fruit juice, or non-diet soda. Your doctor may prescribe glucagon injection in case of severe hypoglycemia.

You may get dehydrated during prolonged illness. Call your doctor if you are sick with vomiting or diarrhea, or if you eat or drink less than usual.

Tell your doctor if you have a planned surgery.

Empagliflozin and Metformin can affect the results of certain medical tests. Tell any doctor who treats you that you are using this medicine.

Your doctor may have you take extra vitamin B12 while you are taking Empagliflozin and Metformin. Take only the amount of vitamin B12 your doctor has prescribed.

Your treatment may also include diet, exercise, weight control, and special medical care.

Store at room temperature away from moisture and heat.

What should I avoid while taking Empagliflozin and Metformin?

Avoid drinking alcohol. It may increase your risk of lactic acidosis.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

Empagliflozin and Metformin side effects

Get emergency medical help if you have signs of an allergic reaction to Empagliflozin and Metformin: hives; trouble swallowing, difficult breathing; swelling of your face, lips, tongue, or throat.

Seek medical attention right away if you have signs of a serious genital infection (penis or vagina): burning, itching, odor, discharge, pain, tenderness, redness or swelling of the genital or rectal area, fever, not feeling well. These symptoms may get worse quickly.

Stop taking Empagliflozin and Metformin and call your doctor at once if you have:

• a light-headed feeling, like you might pass out;
• dehydration - dizziness, confusion, feeling very thirsty, less urination;
• ketoacidosis (too much acid in the blood) - nausea, vomiting, stomach pain, confusion, unusual drowsiness, or trouble breathing;
• lactic acidosis - unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or
• signs of a bladder infection - pain or burning when you urinate, blood in your urine, pain in pelvis or back.

Some side effects may be more likely to occur in older adults.

Common Empagliflozin and Metformin side effects may include:

• low blood sugar;
• indigestion, stomach pain, gas, nausea, vomiting, diarrhea;
• a bladder infection;
• yeast infection in women (vaginal itching or discharge);
• headache, weakness; or
• runny or stuffy nose, sore throat.

What other drugs will affect Empagliflozin and Metformin?

Other drugs may increase or decrease the effects of Empagliflozin and Metformin on lowering your blood sugar. Tell your doctor about all your current medicines and any you start or stop using, especially:

• insulin, or other oral diabetes medicine; or
• a diuretic or "water pill."

This list is not complete. Other drugs may interact with empagliflozin and metformin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.